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Morphine can decrease the efficacy of diuretics by inducing the release of antidiuretic hormone. Morphine may also bring on acute retention of urine by resulting in spasm with the sphincter from the bladder, especially in Guys with enlarged prostates.
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The risk for severe breathing troubles is increased when You begin this medication and following a dose raise, or in case you take the incorrect dose/energy. Getting this medication with alcohol or other drugs which can cause drowsiness or breathing problems may perhaps cause very severe side effects, such as death.
Cimetidine can potentiate morphine-induced respiratory depression. There is actually a report of confusion and severe respiratory depression when a patient going through hemodialysis was concurrently administered morphine and cimetidine.
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If the decision to start morphine sulfate extended-release tablets is made, start out with the lowest possible dose, 15 mg each and every twelve several hours, watch patients for signs of sedation and respiratory depression, and consider employing a lower dose of the concomitant CNS morphine banda depressant [see DRUG INTERACTIONS].
Anaphylaxis has long been noted with elements contained in morphine sulfate extended-release tablets. Recommend patients how to acknowledge this kind of reaction and when to seek medical notice.
Speak to community point out Experienced licensing board or point out managed substances authority for info on how to forestall and detect abuse or diversion of the product or service.
Tell patients that anaphylaxis has been claimed with components contained in morphine sulfate extended-release tablets. Advise patients how to acknowledge this type of reaction and when to seek medical awareness.
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Applying this medicine with any of the next medicines is not encouraged. Your doctor could make your mind up not to treat you with this medication or change several of the other medicines you take.
Give your care crew a list of all medications you employ. He / she will let you know how much medication to take. Never take a lot more medication than directed. Connect with unexpected emergency services in case you have problems breathing.
Take your prescribed dose each individual eight to twelve hours, as directed by your healthcare provider. Usually do not take a lot more than your prescribed dose. When you miss out on a dose, take your future dose at the same old time.